New Paper Accepted

The paper “CTCF regulates NELF, DSIF and P-TEFb recruitment during transcription” has been accepted for publication in the transcription journal Transcription. The first author of this paper is Clelia Laitem (University of Oxford, Shona Murphy lab), who visited our lab and collaborated with us as a JSPS Research Fellow two years ago, and the co-authors

New Paper Accepted

The paper “Characterization of the human transcription elongation factor Rtf1: evidence for non-overlapping Characterization of the human transcription elongation factor Rtf1: evidence for non-overlapping functions of Rtf1 and the Paf1 complex” was accepted for publication in Molecular Cellular Biology and a preliminary version was posted on the web on July 27, 2012. The first author

New Paper Accepted

The paper “SV40 VP1 major capsid protein in its self-assembled form allows VP1 pentamers to coat various types of artificial beads in vitro regardless of their sizes and shapes” has been published in Biotechnology Reports. The first author of the paper is Masaaki Kawano, a graduate of our lab (currently Assistant Professor at Saitama Medical

2014 BBQ

On July 15, 2014, we held a BBQ on the Suzukakedai campus.

New Paper Accepted

The paper “Inhibition of protein SUMOylation by davidiin, an ellagitannin from Davidia involucrata” was published in the Journal of Antibiotics. The first author of the paper is Misao Takemoto (formerly Yoneyama), a former student of our lab who completed the PhD program. This paper has screened a natural product library to identify novel small molecule

New Paper Accepted

The paper “DSIF and NELF interact with Integrator to specify the correct post-transcriptional fate of snRNA genes” has been published in Nature Communications (Nature’s sister journal). The first author of the paper is Junichi Yamamoto, a post-doctoral researcher in our lab. The discovery of the mechanism by which NELF directly interacts with RNA polymerase II,

Gene symbols for NELF subunits

More than a year ago, I received an email from the international committee that determines human gene symbols. Each NELF subunit has unrelated gene symbols that look nonsensical to an outsider, such as WHSC2, COBRA, TH1L, and RDBP. The email asked the researchers involved if it was acceptable to rename them. Since then, the gene

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